NeuroReplete is often used as part of amino acid therapy to help address the underlying neurotransmitter imbalance(s) involved in a number of conditions, including depression, anxiety, OCD, ADD/ADHD, insomnia, cravings and increased appetite, addiction, restless leg syndrome and Parkinson’s disease. NeuroReplete contains the amino acids and cofactors necessary to improve the level and function of serotonin and the catecholamines, which include dopamine, norepinephrine and epinephrine.
NeuroReplete contains the following ingredients:
Vitamin C (ascorbic acid): 500 mg
Calcium (from calcium citrate): 110 mg
Vitamin B6 (as pyridoxine hydrochloride): 37.5 mg
Folate (as folic acid): 200 mcg
L-lysine (as l-lysine hydrochloride): 250 mg
5-Hydroxytryptophan (from Griffonia simplicfolia seed extract): 150 mg
L-tyrosine: 1500 mg
NeuroReplete is a vegetable-based capsule and uses rice flour as a filler/flow agent.
We are often asked if it is possible to gather and take the ingredients listed in NeuroReplete as a cost savings measure. While it is possible, it is difficult to do. The issue comes down to the standardization of the 5-HTP. Very few products labeled as “5-HTP” actually contain significant or standardized amounts of 5-HTP; this has been shown numerous times through third party testing.
The 1:10 ratio of 5-HTTP: L-tyrosine is very important for most people to begin rebalancing their neurotransmitter levels properly. Insuring you get reproducible and standard amounts of those amino acids (along with the necessary cofactors) is essential for long-term success using amino acid therapy. Always keep in mind that the most expensive product is the one that doesn’t work, no matter what the price tag.
Yes, NeuroReplete is expensive; it is also tested to make sure it contains what it says it contains. This step is surprisingly absent in the supplement industry, so it is often well worth the cost to make sure you are getting a good quality product.
I have been on Neuroreplete and cysreplete for over six months would like to wean my self off them now are there directions to do this
Hi Enid – thanks for contacting us; you’ll need to check with your provider to determine the most beneficial taper schedule. Normally, people decrease by 1/2 dose every 2 weeks.
Good luck!
Dr. Chad
Can it be formulated without adding B6? I was very toxic, blood level over 140 then I got it down to 89. That’s when I went back on neuroreplete . Subtle changes developed that I wasn’t aware of until the last lab showed B6 was back up to 100! Bingo! The symptoms of B6 toxicity.
Hi Cynthia – thanks for the comment/question.
You would have to contact the manufacturer directly to voice this concern: http://www.chknutrition.com; we have provided them feedback in the past about possibly using more bio-available forms of the methylated B-vitamins (B6 and folate), but as of yet, there have been no formulation changes –
Good luck!!
Dr. Chad
I started taking NeuroReplete two days ago and am experiencing painful gas and bloating. My stomach hurts too. No nausea. Will this go away?
Hi Christine – you should speak with you provider about this, but it generally indicates that your serotonin levels are quite low. Your provider will likely recommend an altered dosing schedule to bring your levels up more slowly.
Good luck!
Dr. Chad