neuroreplete-1337281500-150x150NeuroReplete is often used as part of amino acid therapy to help address the underlying neurotransmitter imbalance(s) involved in a number of conditions, including depression, anxiety, OCD, ADD/ADHD, insomnia, cravings and increased appetite, addiction, restless leg syndrome and Parkinson’s disease. NeuroReplete contains the amino acids and cofactors necessary to improve the level and function of serotonin and the catecholamines, which include dopamine, norepinephrine and epinephrine.

NeuroReplete contains the following ingredients:

Vitamin C (ascorbic acid): 500 mg

Calcium (from calcium citrate): 110 mg

Vitamin B6 (as pyridoxine hydrochloride): 37.5 mg

Folate (as folic acid): 200 mcg

L-lysine (as l-lysine hydrochloride): 250 mg

5-Hydroxytryptophan (from Griffonia simplicfolia seed extract): 150 mg

L-tyrosine: 1500 mg


NeuroReplete is a vegetable-based capsule and uses rice flour as a filler/flow agent.

We are often asked if it is possible to gather and take the ingredients listed in NeuroReplete as a cost savings measure. While it is possible, it is difficult to do. The issue comes down to the standardization of the 5-HTP. Very few products labeled as “5-HTP” actually contain significant or standardized amounts of 5-HTP; this has been shown numerous times through third party testing.

The 1:10 ratio of 5-HTTP: L-tyrosine is very important for most people to begin rebalancing their neurotransmitter levels properly. Insuring you get reproducible and standard amounts of those amino acids (along with the necessary cofactors) is essential for long-term success using amino acid therapy. Always keep in mind that the most expensive product is the one that doesn’t work, no matter what the price tag.

Yes, NeuroReplete is expensive; it is also tested to make sure it contains what it says it contains. This step is surprisingly absent in the supplement industry, so it is often well worth the cost to make sure you are getting a good quality product.